Bioreactors
This activity can be referred to as a feature unique to SATAKE that is unmatched by any of the commercial production machines.
Realization of Industrialization / Commercial Production / Scalability
Target Scale
Microbial culture / Plant culture | 1L〜3000kL(Higher quantities can also be manufactured) |
---|---|
Animal cell culture SUS Reactor | 0.1L〜15kL(Higher quantities can also be manufactured) |
Animal cell culture SUS Reactor | 0.1L〜200L(As of 2018) |
Reactor made from regenerative medicine glass | 0.1L〜50L |
Regenerative medicine SUB Reactor | 0.1L〜200L(Can be customized as required) |
The scales are for reference purpose only. We will reply with specifications corresponding to your needs.
All-in-one Scale Up Examination Kit
We provide the “All-in-one Scale Up Kit” of our company that undertakes not only laboratory experiments, but also industrialization and commercial production. A scale-up of 500 ml to 10 l is possible with the standard kit, and as an option, a scale-up of up to 50 l can be examined. Note that depending on the demands of the customer, several variations of these configurations are possible. Please contact us. After deciding the specifications, we will customize the equipment and quote you the price. Please be sure to examine the all-in-one scale-up kit that is prepared in accordance with the requirements of the customer.

Can be added up to 50 l as an option
Animal cell BioReactor MRF Reactor

The MRF reactor is a BioReactor for laboratory use that aim at actual production and scaling up. In addition to a “Simple shape with excellent cleaning ability” that is important for the actual equipment, the “MR210Bio impeller used exclusively for cell culture” that exhibits excellent mixing and homogenizing performance is provided as a standard, and therefore, similar culture results as during laboratory experiments can be reproduced during scale-up too. Moreover, fluid surface fluctuation (fed-batch culture) is supported, because of which the same mixing performance is exhibited no matter how much the liquid volume. A wide range of liquid volumes from small volumes like 1.5 L to large volumes of 20,000 l can be supported.
With the help of the dedicated controller “S-BOX × 10α”, changes in various parameters including PI control can be easily performed.
Animal cell BioReactor VMF Reactor
The VMF reactor is a vertical reciprocating motion type next-generation reciprocating mixer for cell culture that combines together excellent blending performance and gentle mixing. Unlike the general rotating type, severe shear stress control is possible. Moreover, a “completely enclosed structure” that does not require a complex rotating-axis seal mechanism is implemented. There is no threat of contamination or leakage, and it has a high level of sterility and cleanliness.
With the help of the dedicated controller “S-BOX × 10α”, changes in various parameters including PI control can be easily performed. Through customization, up to eight machines in series are supported.

Micro-bubble system animal cell culture BioReactor VerSus Reactor

BioReactor VerSus Reactor
The VerSus reactor is a new and innovative BioReactor for animal cell culture in which the technology of “SPG membrane sparger*” by which micro-bubbles with extremely high homogeneity can be generated is fused with a VMF reactor. Through an efficient oxygen supply by the SPG membrane sparger, oxygen can be supplied efficiently without putting stress on the animal cells in the culture tank. Also, due to a decline in the DO air flow rate, a foam layer can be prevented.
With the help of the dedicated controller “S-BOX × 10α”, changes in various parameters including PI control can be easily performed.
Single-use BioReactor
The VMF50L/200L-SUB is a single-use BioReactor for commercial production. A lineup of 50 l to 200 l (proposed to be developed up to 1000 l) is available, and single-use hard bottle/bag that supports sterilization validation is adopted. Since this is a locally-manufactured product, we guarantee just-in-time supply in small lots. With the help of the dedicated controller “S-BOX × 200”, changes in various parameters including PI control can be easily performed.

3D floating iPS cell differentiation induction BioReactor HiD 4 × 4 Reactor

BioReactor HiD 4 × 4 Reactor
The HiD 4 × 4 Reactor is the world’s first “Single-use mixer for 3D floating cell cultures” used exclusively for iPS cell differentiation induction. A BioReactor that achieves a high-volume production of uniform and homogeneous iPS cells is indispensable not only in regenerative medicine, but also in the “Use of human iPS cells in drug development” that aims at industrialization and commercial production. By promoting joint research and development with excellent research institutes or companies in Japan, we have succeeded in commercialization an iPS cell differentiation induction BioReactor for the first time in the world. 4, 8, 12, and 16 (or even more) such BioReactors can be controlled in a consolidated manner, and these are also best suited for screening. Moreover, we have also taken into consideration the adaptation to ES cells while performing development. With the help of the dedicated controller “S-BOX × 02”, changes in various parameters including PI control, and production control in accordance with the purpose can be performed.
Microbial culture / Plant culture HS Turbine



SATAKE takes pride in delivering many culture tanks from small size to large size. Here, we introduce an example of delivery records of large-size cell culture reactors (100 kl to 300 kl class). If you want to order a culture tank as well, the same will be jointly handled by the tank manufacturer working together.
【Motor power】 |
600kW | 480kW | 130kW |
490kW | 470kW | 110kW |
485kW | 430kW | 90kW |
Etc. |

Fully Customized / Exclusive Machines Sold on the Internet
- Construction of a continuous automatic culture medium replacement system
- Long life reactor for regenerative medicine (One-year operation conditions)
- Supply of S-BOX equipped with non-contact sensor “DO/pH” (many performance records in the world)
- Customization of single-use bags (based on computational fluid dynamics)
- Development of small-size closed system
- Supply of a cell culture reactor and culture tank set compliant with GMP validation (up to 5 kl)
If you have any other question, please feel free to contact use anytime.
Fully Customized / Exclusive Machines Sold on the Internet
Contact・Technical Inquiries
Contact
Satake Malaysia office Sales Service Department.
TEL:+603-5525 3171
Email: sales@satakemalaysia.com